[How Long Does Profhilo Last] and When Should I Top Up?

Profhilo has quickly become one of the most in-demand injectable skin boosters in the UK, known for its ability to hydrate, tighten, and rejuvenate the skin without altering facial structure. At SKINLAB, one of the questions we’re most often asked is: how long does Profhilo last, and when should I book my next treatment?


Here’s everything you need to know about maintaining your results and keeping your skin glowing all year round.


Understanding How Profhilo Works

Profhilo is an award-winning injectable made from pure hyaluronic acid, a naturally occurring molecule in the body that attracts and retains moisture. Unlike dermal fillers, Profhilo doesn’t add volume or change facial contours. Instead, it spreads evenly beneath the skin, stimulating collagen and elastin production to restore firmness, elasticity, and radiance.

The result? Smoother, more hydrated skin with improved tone and texture. A true “lit-from-within” glow.

How Long Does Profhilo Last?

After completing your initial course of treatments, Profhilo typically lasts around six months. However, this can vary depending on your skin type, age, metabolism, and lifestyle. Most clients begin to notice visible improvements three to four weeks after their first session, with optimal results appearing after the second session, performed approximately four weeks later.

The results aren’t instant like filler, but they develop gradually as your skin naturally regenerates, leaving you with a fresher, firmer complexion that looks and feels beautifully healthy.

When Should I Have a Profhilo Top-Up?

To maintain your glow, we recommend a Profhilo top-up every six months. For those with mature, dehydrated, or sun-damaged skin, your practitioner may suggest top-ups every four months to maintain elasticity and hydration.

Everyone’s skin responds differently, so your SKINLAB practitioner will tailor a treatment plan specifically for you, ensuring long-lasting results that fit naturally with your skin’s needs.


How Can I Make My Profhilo Results Last Longer?

A few small lifestyle habits can make a big difference in prolonging your Profhilo results:

  • Stay hydrated: Drink plenty of water daily to keep your skin nourished from within.

  • Protect your skin: Use SPF 30+ every day to prevent UV damage that accelerates ageing.

  • Adopt a quality skincare routine: Medical-grade skincare can support collagen and hydration between treatments.

  • Avoid smoking and excess alcohol: Both can deplete hyaluronic acid and collagen, reducing the longevity of your results.

These habits help your skin stay smoother, firmer, and more luminous for longer.

Is There a Right Age to Start Profhilo?

There’s no “perfect” age to begin Profhilo as it’s all about what your skin needs. Many clients in their late 20s to 30s choose Profhilo as a preventative treatment to maintain hydration and elasticity, while those in their 40s, 50s, and beyond love it for its ability to rejuvenate tired, dull skin. Because Profhilo improves overall skin quality rather than altering facial features, it’s suitable for a wide range of ages and skin types.


Profhilo’s FAQs

How many Profhilo sessions do I need?

Most patients begin with two sessions spaced four weeks apart. This allows the hyaluronic acid to integrate evenly while stimulating collagen and elastin for long-lasting results.

Can I combine Profhilo with other treatments?

Yes! Profhilo pairs beautifully with treatments such as microneedling, skin boosters, and light-based therapies to enhance overall rejuvenation and boost collagen production.

Is Profhilo worth it?

Absolutely. Profhilo delivers natural, noticeable improvements in skin hydration, firmness, and radiance, without changing your facial shape or expression.

Is there a right age to start Profhilo?

There’s no set age as it depends on your skin’s needs. Many clients start in their late 20s or 30s to maintain glow and elasticity, while others in their 40s and beyond love it for revitalising and smoothing tired skin.


Profhilo vs Profhilo Structura

As Profhilo continues to lead the way in skin bio-remodelling, a newer, advanced formulation called Profhilo Structura has been developed to target deeper tissue support and lift. While both treatments share the same core technology, they are designed for slightly different purposes and, when used together, they can achieve beautifully balanced, natural results.

Profhilo is ideal for overall skin quality improvement. It works in the superficial layers of the skin to boost hydration, elasticity, and firmness, giving a refreshed and radiant glow. It’s perfect for treating fine lines, crepey texture, and loss of luminosity on the face, neck, and décolletage.

Profhilo Structura, on the other hand, is formulated with a higher density and viscosity, allowing it to act on deeper tissue layers. This makes it particularly effective for restoring support and contour in areas such as the mid-face, cheeks, jawline, and temples. Structura not only enhances hydration but also provides subtle lifting and tightening from within.

At SKINLAB, we often recommend combining both Profhilo and Profhilo Structura as part of a personalised treatment plan — using Profhilo to rejuvenate the skin’s surface while Structura reinforces structure and definition beneath. Together, they deliver a comprehensive approach to facial rejuvenation that looks completely natural.


A Personalised Approach to Beautiful Skin

At SKINLAB, your Profhilo journey begins with a full consultation to assess your skin and discuss your goals. Every treatment is tailored to your unique skin type, ensuring natural-looking results that restore your glow, confidence, and vitality.

Book your Profhilo consultation today and let our experienced practitioners design a treatment plan that keeps your skin looking its best.

Fresh, youthful, and effortlessly radiant.

Book your Profhilo consultation today
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